Elasticity of semiflexible biopolymer networks.
نویسندگان
چکیده
Elasticity of Semiflexible Biopolymer Networks F.C. MacKintosh, ' J. Kas, ' and P. A. Janmey' 'Institute for Theoretical Physics, University of California, Santa Barbara, California 93106-4030 2Department of Physics, University of Michigan, Ann Arbor, Michi an 4M09-1120 3Division of Experimental Medicine, Brigham and Women's Hospital Harv d M d' I S h i, B ar e ica c oo, oston, Massachusetts 02115 (Received 10 July 1995)
منابع مشابه
Scale-dependent non-affine elasticity of semiflexible polymer networks
The cytoskeleton of eukaryotic cells provides mechanical support and governs intracellular transport. These functions rely on the complex mechanical properties of networks of semiflexible protein filaments. Recent theoretical interest has focused on mesoscopic properties of such networks and especially on the effect of local, non-affine bending deformations on mechanics. Here, we study the impa...
متن کامل3 Elasticity of semiflexible polymer networks with flexible cross - links
Recent experiments have demonstrated that the nonlinear elasticity of in vitro networks of the biopolymer actin is dramatically altered in the presence of a flexible cross-linker such as the cytoskeletal protein filamin. The basic principles governing the mechanical properties of such networks, however, remain poorly understood. Here we describe an effective medium theory of flexibly cross-link...
متن کاملEmergent properties of composite semiflexible biopolymer networks.
The semiflexible polymers filamentous actin (F-actin) and intermediate filaments (IF) both form complex networks within the cell, and together are key determinants of cellular stiffness. While the mechanics of F-actin networks together with stiff microtubules have been characterized, the interplay between F-actin and IF networks is largely unknown, necessitating the study of composite networks ...
متن کاملNonlinear Mechanics of Biopolymer Networks
The progress of modern biology demands an interdisciplinary approach to research, bridging the gap between previously disparate fields. This thesis presents a study of the elasticity and microstructure of neurofilaments, which are the primary constituents of neurons, providing the essential mechanical support to resist external stresses. To probe the underlying mechanical properties of neurofil...
متن کاملControl of non-linear elasticity in F-actin networks with microtubules
We measure the elastic properties of composite cytoskeletal networks consisting of cross-linked actin filaments and microtubules. We show that even a small concentration of microtubules leads to dramatic and qualitative changes in the non-linear elastic properties of the actin filament networks. Specifically, we find that microtubules promote non-linear stiffening of F-actin networks because th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Physical review letters
دوره 75 24 شماره
صفحات -
تاریخ انتشار 1995